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Journal: The Laryngoscope
Article Title: Co-Culture of Adipose-Derived Stem Cells and Chondrocytes on Three-Dimensionally Printed Bioscaffolds for Craniofacial Cartilage Engineering
doi: 10.1002/lary.27200
Figure Lengend Snippet: DICOM data of the anatomic structure of interest is acquired and used the generate a three-dimensional model of the structure. The model is then converted into a porous structure using negative Boolean operations and manufactured from polycaprolactone using a selective laser sintering three-dimensional printer. The bioresorbable scaffold is then seeded with cells suspended in a hyaluronic acid/collagen hydrogel prior to implantation. (Adapted from Otolaryngology-Head & Neck Surgery, Volume 152, Issue 1, DA Zopf, AG Mitsak, CL Flanagan, et al. Computer-aided-designed, 3-dimensionally printed porous tissue bioscaffolds for craniofacial soft tissue reconstruction, 57–62, Copyright (2015), with permission from SAGE Publishing).
Article Snippet: The final scaffold design was then 3D printed using an EOS P100 laser sintering system (EOS North America, Novi, Michigan) adapted to
Techniques: